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New Publication !!!
Jiri Pokorny; Clarbruno Vedruccio; Michal Cifra,
PhD.; Ondrej Kucera, Cancer physics: Diagnostics based
on damped cellular elasto‐electrical vibrations in microtubules
(European Biophysics Journal)
2011 March 10
online:
LINK
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Scientific publications related to the diagnostic system
BIOSCANNER TRIMPROB divided in groups
-
First
publication:
- C.Vedruccio and A.Meessen, EM Cancer Detection by Means of Non
Linear Resonance Interaction, Proceedings of PIERS 2004, Progress in
Electromagnetics Research Simposium, Pisa, Italy, March 28-31 2004 :
909-912.
EM Cancer Detection by Means of Non
Linear Resonance Interaction:
doc\Vedruccio-Meessen
PIERS 2004.pdf
Il principio fisico del BIOSCANNER:
doc\Fisica in Medicina 2004.pdf 
- A.Meessen: Working Principle of an EM Cancer Detector; Institut de
Physique, Université Catholique de Louvain, Louvain-la-Neuve, Belgium
(2004)
Cfr. Sito Web:
http://www.meessen.net/AMeessen/EMcancerDet2.pdf
Working Principle of an EM Cancer Detector, August Meessen,
Institut de Physique, Université Catholique de Louvain, 1348 Louvain-la-Neuve,
Belgium: doc\Meessen EMcancerDet2.pdf
-
SCIENTIFIC
BACKGROUND:
C.Vedruccio and A.Meessen, EM Cancer Detection by
Means of Non Linear Resonance Interaction, Proceedings of PIERS 2004,
Progress in Electromagnetics Research Simposium, Pisa, Italy, March 28-31
2004 : 909-912.
-
Fricke, H. and Morse, S. The electric
capacity of tumors of the breast, J. Cancer Res.
10,
340-376, 1926.
doc\Fricke-Morse
1926.pdf
-
Joines, W.T., Jurtle, R.L., Rafal, M.D. and Schaeffer, D.J.
Microwave power absorption differences between normal and malignant tissue,
Int. J. Radiol. Oncology Biol. Phys. 6, 681-7 (1980).
doc\Joines 1980.pdf
- THE SCIENTIFIC PAPER:
European
Biophysics Journal
Online First™ Articles available before print publication
ORIGINAL PAPER
Cancer physics: diagnostics based on damped cellular
elastoelectrical vibrations in microtubules
Jiří Pokorný, Clarbruno Vedruccio, Michal Cifra and Ondřej
Kučera
Online First™, 2011 March 10
http://www.springerlink.com/content/577757274043rk07/
*Institute of Photonics and Electronics, Academy of Sciences of the Czech
Republic , Praga.
Abstract
This paper describes a proposed biophysical mechanism of a novel
diagnostic method for cancer detection developed recently by
Vedruccio. The diagnostic method is based on frequency selective
absorption of electromagnetic waves by malignant tumors. Cancer
is connected with mitochondrial malfunction (the Warburg effect)
suggesting disrupted physical mechanisms. In addition to
decreased energy conversion and nonutilized energy efflux,
mitochondrial malfunction is accompanied by other negative
effects in the cell. Diminished proton space charge layer and
the static electric field around the outer membrane result in a
lowered ordering level of cellular water and increased damping
of microtubule-based cellular elastoelectrical vibration states.
These changes manifest themselves in a dip in the amplitude of
the signal with the fundamental frequency of the nonlinear
microwave oscillator—the core of the diagnostic device—when
coupled to the investigated cancerous tissue via the near-field.
The dip is not present in the case of healthy tissue.
Keywords Cancer diagnostics – Bioscanner® TRIMprob™ – Physical
processes in cancer – Biological electromagnetic field – Water
ordering in cells – Nonlinear resonance interaction (NLRI)
- Non-thermal effects and mechanisms of interaction between
electromagnetic fields and living matter. a cura di L. Giuliani,
M. Soffritti
Clarbruno Vedruccio: Polarizability
of normal and cancerous tissues, a Radiofrequency Nonlinear
Resonance Interaction non invasive diagnostic Bioscanner Trimprob
detector alle pagg.177-185.
doc\Eur.J.
Oncol 2010-0.pdf
-
Clinical
trials
papers on PUBMED (Database of the National Institute of Health U.S.A.,
medical publications with impact factor) to
see the abstracts site: http://www.ncbi.nlm.nih.gov/pubmed/ (Search:
Trimprob)
- Alberto Vannelli, Luigi Battaglia, Elia Poiasina and Ermanno Leo, Diagnosis
of rectal cancer by Tissue Resonance Interaction Method, BMC
Gastroenterology 2010, 10:45.
Division of General Surgery B, Fondazione IRCCS Istituto Nazionale Tumori,
Milan, Italy
http://www.biomedcentral.com/1471-230X/10/45
doc\TRIM
Rectal Cancer 2010.pdf
PUBMED IN PROGRESS
-
Di Viccaro D,
Perugia G, Cerulli C, Olivieri V, Bova J, Zanza C, Teodonio S, Liberti
M.
The accuracy of tissue resonance interaction method probe (Trimprob tm)
in non-invasive diagnosis of prostatic cancer. Analysis of the results
of 782 patient.
Urologia. 2009;76 Suppl 15:1-3. PubMed PMID: 21104675.
doc\2009 Di Vaccaro-Cerulli Riv_Urologia_.pdf
- O. Gokce, O. Sanli, A. Salmaslioglu, A. Tunaci, C. Ozsoy and F. Ozcan,
Tissue Resonance Interaction Method (TRIMprob) has the potential to be
used alongside the recognized tests in the screening protocols for
prostate cancer, International Journal of Urology (Int J Urol.), 2009
Jun;16(6):580-3.
doc\Int J Urol Turch
2009.pdf
(Clinical Trials carried out at The Departments of Urology and
Radiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul,
Turkey)
- Vannelli A, Leo E, Battaglia L, Poiasina E., Diagnosis of rectal
cancer by electromagnetic interactions: preliminary results, Dis Colon
Rectum. 2009 Jan;52(1):162-6. (Clinical Trials carried out at Istituto
Nazionale dei Tumori - National Cancer Institute - Milan Italy)
doc\Ist
Tum Mi Trimprob-rectal cancer 2009.pdf
- Tubaro A, De Nunzio C, Trucchi A, Stoppacciaro A, Miano L., The
electromagnetic detection of prostatic cancer: evaluation of diagnostic
accuracy. Urology. 2008 Aug;72(2):340-4. (Clinical Trials carried out at
The Sapienza University – Sant'Andrea Hospital Roma Italy)
doc\TRIMprob Urology
2008.pdf
- Sacco R, Sammarco G, De Vinci R, Vescio G, Scarpelli A, Lucisano AM,
Pata F, Mascia E, Martines V.,Relief of gastric cancer with an
electromagnetic interaction system (TRIMprob) in outpatients. Chir Ital.
2007 Nov-Dec;59(6):823-8. (Clinical Trials carried out at Magna
Graecia-University– Mater Domini Hospital– Catanzaro Italy)
- Da Pozzo L, Scattoni V, Mazzoccoli B, Rigatti P, Manferrari F,
Martorana G, Pietropaolo F, Belgrano E, Prezioso D, Lotti T, Villari D,
Nicita G.,Tissue-resonance interaction method for the noninvasive
diagnosis of prostate cancer: analysis of a multicentre clinical
evaluation. BJU Int. 2007 Nov;100(5):1055-9. (Five University
Multicentre Clinical Trials carried out at: S.Raffaele Milan, Federico
II Naple, Careggi Florence, S.Orsola-Malpighi Bologna, Cattinara Trieste
- Italy)
- Gervino G, Autino E, Kolomoets E, Leucci G, Balma M., Diagnosis of
bladder cancer at 465 MHz. Electromagn Biol Med. 2007;26(2):119-34.
(Clinical Trials carried out at Vito Fazzi Hospital – Lecce Italy)
- Sacco R, Innaro N, Pata F, Lucisano AM, Talarico C, Aversa S.,Preoperative
diagnosis of incidental carcinoma in multinodular goitre by means of
electromagnetic interactions Chir Ital. 2007 Mar-Apr;59(2):247-51.
(Clinical Trials carried out at Magna Graecia-University– Mater Domini
Hospital– Catanzaro Italy)
- De Cicco C, Mariani L, Vedruccio C, Ricci C, Balma M, Rotmensz N,
Ferrari ME, Autino E, Trifirò G, Sacchini V, Viale G, Paganelli G.,
Clinical application of spectral electromagnetic interaction in breast
cancer: diagnostic results of a pilot study. Tumori. 2006 May-Jun;92(3):207-12.
(Clinical Trials carried out at The European Institute of Oncology –
I.E.O.- Milan Italy)
http://www.tumorionline.it/index.php?archivio=yes&vol_id=234
doc\Breast
IEO Tumori 2006.pdf
- Bellorofonte C, Vedruccio C, Tombolini P, Ruoppolo M, Tubaro A.,
Non-invasive detection of prostate cancer by electromagnetic interaction.,
Eur Urol. 2005 Jan;47(1):29-37; discussion 37. (Clinical Trials carried
out at the San Carlo Hospital - Milan Italy)
doc\Eur Urol 2005.pdf
-
Physics
and Biophysics papers relative to the principles of operation:
- C. Vedruccio, A. Meessen, Nuove possibilità diagnostiche tramite onde
elettromagnetiche, Fisica in Medicina (AIFM), 3: 225-230, 2004C.
- Vedruccio, Ultra High Frequency and Microwave Non-linear
Interaction Device for Cancer Detection and Tissue Characterization,
Proc. of Augmented Reality in Surgery, 1st European Summer School (ARISER)
IFC-CNR , Lecce, Italy, July 4th-8th 2005: 8-12.
- C.Vedruccio, Non-linear Resonance Interaction. The Trimprob clinical
trials , Minimally Invasive Therapies & Novel Embedded Technology
Systems, The Text Book of The 2st European Summer School (ARISER)
IFC-CNR , Santa Cesarea Terme (Le)Italy, July 17th-21th 2006: 119-132.
- C.Vedruccio, C.Ricci, The Trimprob Non Linear Resonance Interaction
for early Cancer Detection, Casciaro S. and Samset E. (Eds.) 2007,
Minimally Invasive Therapies and Novel Embedded Technologies, Lupiensis
Biomedical Publications , Lecce, 2007:111-118.
- C.Vedruccio, Non Linear Resonance Interaction. Some New Applications
of the Trimprob for Cancer Detection on Stomach-Duodenum and Other
Organs, Casciaro S. and Samset E. (Eds.), Minimally Invasive Therapies
and Novel Embedded Technologies, Lupiensis Biomedical Publications,
Lecce, 2007:22-26.
- C.Vedruccio, Polarizability of normal
and cancerous tissues, a Radiofrequency Nonlinear Resonance Interaction non
invasive diagnostic Bioscanner Trimprob detector, in L. Giuliani,
M. Soffritti (Eds). Non-thermal effects and mechanisms of interaction
between electromagnetic fields and living matter, Mattioli 1885 spa,
Fidenza, 2010: pagg.177-185. European
Journal of Oncology - Library Vol. 5
(National Institute for the Study and Control of Cancer and Environmental
Diseases “Bernardino Ramazzini” Bologna, Italy.
-
Clinical
trials related scientific publications (not PUBMED indexed):
- C. Vedruccio, E. Mascia, V. Martines, Ultra High Frequency and
Microwave Non-linear Interaction Device for Cancer Detection and Tissue
Characterization , a Military Research approach to prevent Health
Diseases, International Review of the Armed Forces Medical Services (IRAFMS),
vol 78/2: 120-126( 2005) .
doc\Stomaco IRAFMS 2005.pdf
- Bellorofonte et al., Il Trimpob: un nuovo mezzo diagnostico non
invasivo nel carcinoma prostatico dell’anziano, Cancer and Aging, vol. 3
n.1: 31-36 (2005).
- A.M. Lucisano, N. Innaro, F. Pata, R.Sacco, Diagnosis of Carcinoma
in Multinodular Goiter by Electromagnetic Interactions. Preliminary
Results. European Surgical Research 2006; 38:129-312.
-
Divulgative
publications
(
To be completed)
- Umberto Veronesi, La prostata? Per salvarla c’è un’arma in
più.Mensile Oggi, n.5 febbraio 2006
(A cura di Edoardo Rosati)
- Settimanale "Oggi" del 5 febbraio 2006:
doc\trimprobe Veronesi light.pdf
Intervista a Clarbruno Vedruccio a cura di Stefano Lorenzetto (Rubrica
Tipi Italiani) su Il Giornale del 14 marzo 2010 dal titolo “Ha inventato la
macchina che vede i tumori: lo accusano di stregoneria”. (IN PROGRESS)
http://www.ilgiornale.it/interni/ha_inventato_macchina_che_vede_i_tumori_accusano_stregoneria/14-03-2010/articolo-id=429339-page=0-comments=2
doc\Il Giornale 14
marzo 2010.pdf
http://www.lastampa.it/_web/CMSTP/tmplrubriche/giornalisti/grubrica.asp?ID_blog=124&ID_articolo=986&ID_sezione=274&sezione=
Research doctorate
• Dott. Cosimo De Nunzio, Urologia, Università La Sapienza, Roma
• Dott. Luca Ronci, Urologia, Università Alma Mater Studiorum, Bologna
• Dott.ssa Ai Ling Romanò, Urologia, Università Statale, Milano
• Dott. Filippo Calzolari, Chirurgia, Seconda Università, Napoli
RESEARCH DOCTORATE IN
PROGRESS
POSTERS AND
CONGRESS
M. Tufano, C. Vedruccio, Principi e applicazioni cliniche del TRIMprob in
diagnostica. 41° Congresso Nazionale SIRM (Società Italiana per la
Radiologia Medica), maggio 2004, Palermo.
L. D'Urso et al. Renal Cancer Detection with a New Non Invasive
Diagnostic Tool (TRIMprob): A
SCUP Pilot Study. 19th EAU Meeting, Maggio 2004, Vienna
C. Bellorofonte et al. La Risonanza Elettromagnetica Non-Lineare nella
Diagnostica delle Patologie
Prostatiche. 77° Congresso SIU, Giugno 2004, Milano
B. Rocco et al. Sensibilità e Valore Predittivo Negativo della Biopsia
Prostatica ed Esperienza
Preliminare con TRIMprob. 77° Congresso SIU, Giugno 2004, Milano
V. Martines. TRIMprob: from Military Technology a Weapon for the Defense of
Health. Preliminary
Report. 35th International Congress on Military Medicine, Settembre 2004,
Washington
L. D'Urso et al. Diagnosi di Neoplasia Renale con un Nuovo Metodo Non
Invasivo (TRIMprob): uno
Studio Pilota dello SCUP. 14° Congresso SIURO, Dicembre 2004, Trieste
R. Bartoletti et al. Significato dell’Esame TRIMprob nella Diagnostica dei
Pazienti Affetti da
Carcinoma Prostatico Sottoposti a 2 o più Sequenze Bioptiche. 14° Congresso
SIURO, Dicembre
2004, Trieste
G. Leucci et al. Studio Pilota per la Diagnosi del Carcinoma Vescicale
mediante l’Utilizzo del
TRIMprob. Dati Preliminari. XI Congresso Nazionale AUROIT, Ottobre 2004,
Lecce, e 6°
Congresso SUN, Novembre 2004, Bari
XI NATIONAL CONGRES AUROIT, LECCE,
6 – 9 OTTOBRE 2004:
doc\Congr XI AURO vescica1
2004.pdf
C. Bellorofonte et al. The Accuracy of the TRIMprob for the Diagnosis of
Prostate Cancer: Two-
Year Experience. 20th EAU Meeting, Marzo 2005, Istanbul:
PosterIstanbul.pdf
C. Bellorofonte et al. The Accuracy of the TRIMprob for the Diagnosis of
Prostate Cancer. AUA
2005 Annual Meeting, Maggio 2005, USA
A. Stoppacciaro et al. The Effect of the TRIMprob on the Patient Population
Selected for Prostate
Biopsy and Biopsy Outcome. 78° Congresso SIU, Giugno 2005, Palermo
C. Rotondo et al. Utilizzo del TRIMprob nella Diagnosi del Carcinoma
Vescicale: Esperienza
Preliminare. 15° Congresso SIURO, Novembre 2005, Giardini Naxos
A. Tubaro et al. Early Diagnosis of Prostate Cancer: TRIMprob versus PSA,
DRE and TRUS: a
Toss-up Controlled Study. 21st EAU Meeting, Aprile 2006, Paris
L. Da Pozzo et al. Tissue Resonance Interaction Method for Non Invasive
Diagnosis of Prostate
Cancer: A Multicenter Clinical Evaluation. 21st EAU Meeting, Aprile 2006,
Paris
C. De Nunzio et al. TRIMprob, PSA, ER ed Ecografia nella Diagnosi del Tumore
Prostatico. Studio
Clinico Controllato verso la Legge del Caso. 79° Congresso SIU, Giugno 2006,
Bologna
L. Da Pozzo et al. Tissue Resonance Interaction Method nella Diagnosi Non
Invasiva del
Carcinoma Prostatico: Risultati di uno Studio Prospettico Multicentrico. 79°
Congresso SIU,
Giugno 2006, Bologna
A.M. Lucisano, N. Innaro, F. Pata, R. Sacco. Diagnosis of Carcinoma in
Multinodular Goiter by
Electromagnetic Interactions. Preliminary Results. 19° Congresso Nazionale
dell’Italian
Polyspecialist Society of Young Surgeons (IPSYS), Giugno 2006, Bologna
R. Sacco et al. TRIMprob, a New Diagnostic Tool in Cancer Detection.
Workshop. 3rd Cancer
Conference of the African Oncology Institute, Gennaio 2007, Sabratha (Libia)
P. Cialone (Col.). Il Ruolo del TRIMprob nella Diagnosi del Carcinoma della
Prostata. Focus on:
“Carcinoma della Prostata”. Attualità Diagnostiche e Terapeutiche, Marzo
2007, Roma
G. De Giorgi et al. Utilizzo del TRIMprob nella Diagnostica Non Invasiva del
Tumore Prostatico.
80° Congresso SIU, Settembre 2007, Bari, e 17° Congresso SIURO, Novembre
2007, Modena
R. Ballario et al. TRIMprob e Biopsia Prostatica. Risultati di uno Studio
Prospettico ‘Single Blind’.
XIV Congresso AUROIT, Ottobre 2007, Firenze, e 17° Congresso SIURO, Novembre
2007,
Modena
P. Viganò, G.R. Strada. TRIMprob nella Diagnostica Non Invasiva del
Carcinoma Prostatico:
Esperienza Personale. 17° Congresso SIURO, Novembre 2007, Modena
A. Cicione, C. De Nunzio et al. TRIMprob for the Electromagnetic Detection
of Prostate Cancer:
Accuracy Evaluation. 20° Congresso Nazionale dell’Italian Polyspecialist
Society of Young
Surgeons (IPSYS), Novembre 2007, Napoli
F. Pata, A.M. Lucisano, D.P. Pafundi, R. Sacco. TRIMprob in Diagnosis of
Bladder Cancer:
Preliminary Results. 20° Congresso Nazionale dell’Italian Polyspecialist
Society of Young
Surgeons (IPSYS), Novembre 2007, Napoli
F. Carrozza. Possibile Utilizzo del TRIMprob nella Diagnostica del Cancro
Mammario. Workshop
Oncologico Pratico Militare, Novembre 2007, Roma
http://www.icems.eu/docs/venice/6th_Workshop_Carrozza.pdf
A. Barbarisi et al. TRIMprob Radiation Interaction with Prostate Cells:
Effect on Cellular Activity
and Implication for Carcinoma Diagnosis. 11° Conferenza Annuale dell’ESS
(European Society of
Surgery), Novembre-Dicembre 2007, Krakow (Polonia)
Marcello Tufano: XVII
National Congress of Digestive Diseases (Gastro-enterology), 5 to 9
March 2011, Torino, Poster Session:
"The
Accuracy of the BIOSCANNER TRIMPROB®, a non-invasive tool,
for the diagnosis of Colon Cancer. A Double blind
prospective study".
EXPERIMENTAL STUDY IN NUDE MICE
- "The Sapienza University", Dept. of Urology, Sant’Andrea
Hospital, Rome, Italy, , Dept. of Pathology, Rome, Italy, National Cancer
Institute “Regina Elena”, Laboratory for Preclinical Experimental Chemotherapy,
Rome, Italy
Tubaro A.1, De Nunzio C.1, Stoppacciaro A.2, Leonetti C., Zupi G., Miano L.1
Ospedale Sant’Andrea, “La Sapienza University”, Dept. of Urology, Rome,
Italy, 2Ospedale Sant’Andrea, “La Sapienza University”, Dept. of Pathology,
Rome, Italy, National Cancer Institute “Regina Elena”, Laboratory for
Preclinical Experimental Chemotherapy, Rome, Italy
830 - AN EXPERIMENTAL
STUDY IN NUDE MICE ON THE ELECTROMAGNETIC DIAGNOSIS OF TUMOURS, Eur Urol
Suppl 2008;7(3):278
Abstr
830-Tubaro mice 2008.pdf
Eur Urol.mice
2008.pdf
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